BioTools

Press Release Chiral Technologies & BioTools Partner up

btadmin — Wed, 10 Aug 2011 16:46:11 +0000

Hot Topics VOA

btadmin — Wed, 17 Nov 2010 03:18:10 +0000

Dear Researchers,

As the VOA field expands, periodically we
will be featuring papers published in the field.

Recent Published VOA Papers

Absolute configuration reassignment of two chromanes from Peperomia obtusifolia (Piperaceae) using VCD and DFT calculations

João Marcos Batista Jr. _a,e, Andrea N. L. Batista _a, Daniel Rinaldo _a, Wagner Vilegas _a, Quezia B. Cass _b, Vanderlan S. Bolzani _a, Massuo J. Kato _c, Silvia N. López _a,d, Maysa Furlan _a, Laurence A. Nafie _e*

a Instituto de Química, Departamento de Química Orgânica, UNESP, Univ Estadual Paulista, C.P. 355, 14800-900, Araraquara, SP, Brazil

b Departamento de Química, Universidade Federal de São Carlos, UFSCar, C.P. 676, 13565-905, São Carlos, SP, Brazil

c Instituto de Química, Universidade de São Paulo, USP, Prof. Lineu Prestes 748 b 11 T, São Paulo, SP, Brazil

d Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK, Rosario, Argentina

e Department of Chemistry, 1-014CST, Syracuse University, Syracuse, NY 13244-4100, USA

Tetrahedron: Asymmetry 21 (2010) 2402-2407

DOI: 10.1016/j.tetasy.2010.09.004

Direct observation and pH control of reversed supramolecular chirality in insulin fibrils by vibrational circular dichroism

Dmitry Kurouski,_bRosina A. Lombardi,_aRina K. Dukor,_cIgor K. Lednev*_band

Laurence A. Nafie*_ac

_a Department of Chemistry, Syracuse University, Syracuse, New York,13244, USA. E-mail: lnafie@syr.edu

_b Department of Chemistry, University at Albany, SUNY, 1400 Washington Ave., Albany, NY 12222, USA. E-mail: lednev@albany.edu

_c BioTools, Inc., 17546 Bee Line Hwy, Jupiter, Florida, 33458, USA. E-mail: rkdukor@aol.com

Chem. Commun., 2010, 46, 7154-7156

DOI: 10.1039/c0cc02423f

Chirality transition in the epoxidation of (_)-a-pinene and successive hydrolysis studied by Raman optical activity and DFT

Shi Qiu,_abGuanna Li,_abPeng Liu,_abChanghao Wang,_abZhaochi Feng*_aand

Can Li*_a

_a State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. E-mail: zcfeng@dicp.ac.cn, canli@dicp.ac.cn; Fax: +86-411-84694447; Tel: +86-411-84379303, +86-411-84379070

_b Graduate University of Chinese Academy of Sciences, Beijing, 100049, China

Phys. Chem. Chem. Phys., 2010, 12, 3005-3013

DOI: 10.1039/b919993d

Vibrational Circular Dichroism of Adsorbed Molecules: BINAS on Gold Nanoparticles

Cyrille Gautierand Thomas Buürgi*

Institut de Physique, Laboratoire de Chimie Physique des Surfaces, UniVersité de Neuchâtel, Rue Emile-Argand

11, 2009 Neuchâtel, Switzerland, and Physikalisch-Chemisches Institut, Ruprecht-Karls-UniVersität Heidelberg,

Im Neuenheimer Feld 253, 69120 Heidelberg, Germany

J. Phys. Chem. C 2010, 114, 15897-15902

DOI: 10.1021/jp910800m

Theoretical Raman Optical Activity Study of the β Domain of Rat Metallothionein

Sandra Luber and Markus Reiher*

Laboratorium für Physikalische Chemie, ETH Zürich, Wolfgang-Pauli-Str. 10, CH-8093 Zürich, Switzerland

J. Phys. Chem. B 2010, 114, 1057-1063

DOI: 10.1021/jp909483q

Directly Probing the Racemization of Imidazolines by Vibrational Circular Dichroism: Kinetics and Mechanism

Shengli Ma, Carl A. Busacca, Keith R. Fandrick, Teresa Bartholomeyzik,

Nizar Haddad, Sherry Shen, Heewon Lee, Anjan Saha, Nathan Yee,

Chris Senanayake, and Nelu Grinberg*

Department of Chemical DeVelopment, Boehringer Ingelheim Pharmaceuticals, Inc.,

Ridgefield, Connecticut 06877

nelu.grinberg@boehringer-ingelheim.com

Org. Lett., Vol. 12, No. 12, 2010

DOI: 10.1021/ol100734t

Side Chain and Flexibility Contributions to the Raman Optical Activity Spectra of a Model Cyclic Hexapeptide

Jana Hudecová,Josef Kapitán,Vladimír Baumruk,Robert P. Hammer,

Timothy A. Keiderling,*and Petr Bouř*

Institute of Organic Chemistry and Biochemistry, Academy of Sciences, FlemingoVo nám. 2,

Prague 6, 16610, Czech Republic, Institute of Physics, Charles UniVersity, Ke KarloVu 5, 12116, Prague 2,

Czech Republic, Department of Chemistry, Louisiana State UniVersity, 232 Choppin Hall, Baton Rouge,

Louisiana 70803-1804, and Department of Chemistry, UniVersity of Illinois at Chicago, 845 West Taylor Street, Chicago Illinois 60607-7061

J. Phys. Chem. A 2010, 114, 7642-7651

DOI: 10.1021/jp104744a

Determining the structure of α-phenylethyl isocyanide in chloroform by VCD spectroscopy and DFT calculations-simple case or challenge

Christian Merten,* Marc Amkreutz and Andreas Hartwig

Fraunhofer Institute for Manufacturing Technology and Applied

Materials Research (IFAM), Wiener Strasse 12, 28359 Bremen,

Germany. E-mail: christian.merten@ifam.fraunhofer.de;

Fax: +49 421 2246 430; Tel: +49 421 2246 515

Phys. Chem. Chem. Phys., 2010, 12, 11635-11641

DOI: 10.1039/c004009f

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Ec2 Brochure

btadmin — Wed, 17 Nov 2010 03:12:13 +0000

Ec2 Brochure 1

Ec2 Brochure 2

Hot Topics VOA

btadmin — Wed, 03 Nov 2010 01:22:15 +0000

Dear Researchers,

As the VOA field expands, we will be featuring
papers published in the field periodically.

Recent Published VOA Papers

Vibrational optical activity

Laurence D. Barron a,*, A. David Buckingham b

a Department of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK

b Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK

Chemical Physics Letters 492 (2010) 199-213

doi:10.1016/j.cplett.2010.03.090

A novel computational method for comparing vibrational

circular dichroism spectra

Jian Shen, Chengyue Zhu, Stephan Reiling, Roy Vaz

Chemical and Analytical Science, Sanofi Aventis Inc., 1041 Route 202-206, Bridgewater, NJ 08807, USA

Spectrochimica Acta Part A 76 (2010) 418-422

doi:10.1016/j.saa.2010.04.014

Absolute configuration of tropane alkaloids from Schizanthus

species by vibrational circular dichroism

Matías Reina _a, Eleuterio Burgueño-Tapia _b, María A. Bucio _c, Pedro Joseph-Nathan _c

a Instituto de Productos Naturales y Agrobiología (IPNA), CSIC, La Laguna, Tenerife, Spain

b Departamento de Química Orgánica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,

Prolongación de Carpio y Plan de Ayala, Col. Santo Tomás, México, D.F., 11340, Mexico

c Departamento de Química, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico

Nacional, Apartado 14-740, México, D.F., 07000, Mexico

Phytochemistry 71 (2010) 810-815

doi:10.1016/j.phytochem.2010.02.004

Conformations of Phenylalanine in the Tripeptides AFA and

GFG Probed by Combining MD Simulations with NMR, FTIR,

Polarized Raman, and VCD Spectroscopy

Silvia Pizzanelli*_{a b}, Claudia Forte _{a b}, Susanna Monti_{a b}, Giorgia Zandomeneghi,_c

Andrew Hagarman _{a b}, Thomas J. Measey _{a b}, and Reinhard Schweitzer-Stenner _{a b}

Istituto per i Processi Chimico Fisici, Consiglio Nazionale delle Ricerche, Area della Ricerca di Pisa, Via G. Moruzzi, 1 56124

Pisa, Italy, Department of Chemistry, Drexel UniVersity, 3141 Chestnut Street, Philadelphia, PennsylVania 19104, and

Laboratory of Physical Chemistry, ETH-Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland

_a Area della Ricerca di Pisa, _bDrexel University, _cETH-Zurich
J. Phys. Chem. B 2010, 114, 3965-3978

doi: 10.1021/jp907502n

Conformational analysis and vibrational circular dichroism

study of a chiral metallocene catalyst

Christian Merten *, Marc Amkreutz, Andreas Hartwig

Fraunhofer Institute for Manufacturing Technology and Applied Materials Research (IFAM), Wiener Strasse 12, 28359

Bremen, Germany

Journal of Molecular Structure 970 (2010) 101-105

doi:10.1016/j.molstruc.2010.02.052

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BioTools Celebrates 10 Years!

btadmin — Sun, 17 Oct 2010 07:32:35 +0000

BioTools Inc is celebrating its 10-year
anniversary in 2010. From the start, we
dared to be unique, innovative, and
customer- driven and commercialized two
groundbreaking techniques – VCD and ROA.
We thank everyone who helped us along the
way – customers, vendors and friends.
We invite you to partner with us as we look to
the future and continue to revolutionize the
forefront of vibrational spectroscopy.

17546 Bee Line Hwy ? Jupiter, FL 33458 USA
Tel: 561-625-0133 ? Toll Free: 866-BTOOLS1 ? Fax: 561-625-0717
Email: info@btools.com ? website: www.btools.com

BioTools announces establishment of BioTools Europe

btadmin — Sun, 17 Oct 2010 06:00:24 +0000

Contact: Rina Dukor, Ph.D.
Bee Line Highway
BioTools, Inc.
Jupiter, Florida 33458 USA
Phone: (561) 625-0133
E-mail: info@btools.com
Fax: (561) 625-0717
Website: www.btools.com/europe/
Press Release

BioTools, Inc. expands to Europe; announces establishment of
BioTools Europe, Ltd.

Jupiter, Florida, USA January 5, 2010: BioTools, Inc. proudly announces the
establishment of its first international subsidary, BioTools Europe, Ltd.
BioTools’ core technologies, Vibrational Circular Dichroism (VCD) and Raman Opitcal
Activity (ROA), have seen significant growth over the past few years. This provides a
strong base for continued growth as we expand our products and services. VCD has
become a standard technique for the determination of absolute configuration of chiral
molecules whereas ROA, an exclusive product to BioTools, is pimarily used as a senrsitive
probe for structural elucidation of biomolecules. Customers for both techniques include
academic institutions, regulatory agencies and pharmaceutical companies. European
markets account for a large percentage of this growth. The establishment of its own
European subsidary enhances BioTools capability to improve its regional support
delivering an even higher standard of service to its customers. .
BioTools Europe Ltd is headquartered in Surrey, UK, south of London, where Mr. Frank
Trundle serves as Managing Director of BioTools Europe and as Vice President of
BioTools, Inc. Mr. Trundle brings with him over 20 years experience in international
high-technology-based instrumentation business. ”We are very fortunate to have Frank as
our leader in Europe. Frank’s experience in sales, marketing, and business, and product
development is a tremendous asset to our rapidly growing company. We are priveleged to
have him on board.” says Dr. Rina Dukor, Ph.D, President of BioTools, Inc.
About BioTools, Inc.
BioTools is a world leader in providing advanced instrumentation and services to
pharmaceutical companies and academia serving critical areas of biopharmaceutical and
chiral drugs research. Its unique products are used for molecular structure characterization
from basic research to formulated finished products. Founded in 2000, BioTools has R&D,
sales, customer support, contract research lab and manufacturing facilities in Jupiter,
Florida and now sales and customer support in Surrey, UK.

Welcome to BioTools – BTools.com!

btadmin — Sun, 17 Oct 2010 02:36:09 +0000

Please take a moment to get familiar with our new layout. If you have any questions or feedback about the site please contact us.

Partners

btadmin — Wed, 13 Oct 2010 06:24:21 +0000

ABB Bomem

585 Charest Blvd, Suite 300
Quebec, Canada G1K 9H4

Phone: (418) 877-2944
Fax: (418) 877-2834
North America: (800) 858-FTIR
www.abb.com/analytical

All of our infrared products incorporate ABB Bomem interferometers, allowing for superior accuracy and permanent alignment. BioTools also acts as a local representative for the ABB FT-IR/NIR Analyzers.

Critical Link

Critical Link, LLC
251 Saline Meadows Pkwy
Syracuse, NY 13212

Voicemail: (315) 425-4045
Fax: (315) 425-4048
www.criticallink.com

Critical Link is an engineering firm that works closely with the BioTools team to produce the most innovative line of Raman products.

Gaussian, Inc.

340 Quinnipiac St Bldg 40
Wallingford, CT 06492 USA

Phone: (203) 284-2501
Fax: (203) 284-2521
www.gaussian.com

We use and recommend Gaussian 09 for VCD and ROA calculations.

Laser Quantum

Emery Court
Vale Road
Stockport
Cheshire
SK4 3GL
United Kingdom (UK)

Phone: +44 (0) 161 975 5300
Fax: +44 (0) 161 975 5309
www.laserquantum.com

We use and recommend Laser Quantum lasers.