Archive for the News Category

Dr. Rina Dukor is featured in spring 2013 issue of AtLAS

AtLAS Spring 2013 Edition
“From Russia with Love, Learning and Entrepreneurial Spirit

rina-atlas“I come from a family of medical professionals and engineers—my mother was a civil engineer—so it came to me naturally,” said Department of Chemistry alumna Rina Dukor (BS ’86, MS ’87, PhD ’91). “But in Russia when I was growing up, there was a lot of discrimination against Jews. It would have been almost impossible to get into a good university. My mother knew I would never reach my full potential if we stayed, so we emigrated to the U.S.

“All the Russians in Chicago settled along Devon Avenue in Rogers Park and either went to Mather or Sullivan High School. I started at Sullivan in October 1980 and graduated a year and a half later. I had a really fun chemistry teacher and because of him truly fell in love with science.”

Dukor is now the President of BioTools, Inc., a company that provides advanced instrumentation and services to pharmaceutical companies and academics engaged in biopharmaceutical and drug research. Their products include the Chiral-RAMAN-2X™ Raman Optical Activity spectrometer, for which they won a 2004 R&D 100 Award, and the ChiralIR-2X™ Vibrational Circular Dichroism (VCD) spectrometer. Read More!

*AtLAS is a UIC, College of Liberal Arts & Sciences publication.


Prof. Laurence Nafie receives Pittsburgh Spectroscopy Award at Pittcon 2013

Pittcon Conference – March 13, 2013


During the 2013 Pittcon conference Prof. Laurence Nafie, Distinguished Emeritus Professor at Syracuse University and co-founder of BioTools, Inc., was honored for his achievements in vibrational optical activity by receiving the Pittsburgh Spectroscopy Award presented by the Spectroscopy Society of Pittsburgh (SSP) and presenting a lecture entitled, “Vibrational Optical Activity: A Mature New Field Of Vibrational Spectroscopy.”

The 2013 Pittsburgh Spectroscopy Award presented by the Spectroscopy Society of Pittsburgh (SSP). The SSP Award, established in 1957, honors an individual who has made outstanding contributions in the field of spectroscopy. Laurence A. Nafie received his Ph.D. from the University of Oregon in 1973. He was a postdoctoral associate at the University of Southern California until 1975, when he joined the faculty at Syracuse University. Currently he is Emeritus Distinguished Professor at Syracuse University and Editor-in-Chief of the Journal of Raman Spectroscopy.



BioTools names John Shea to position of Vice President of Sales

Press Release, Jupiter, FL – March 2013

BioTools names John Shea to position of Vice President of Sales


BioTools, Inc. is pleased to announce the appointment of Mr. John Shea as Vice President of Sales.  John brings with him nearly 20 years of professional experience in molecular spectroscopy and will be responsible for all sales activity in North America. He previously served as Director of North American Molecular Sales for Nicolet Instruments / Thermo Electron Corporation.

“We are very fortunate and excited to have someone of John’s caliber and experience join BioTools. John’s knowledge and technical expertise is a tremendous asset for the growth of the company.” said Dr. Rina K. Dukor, President of BioTools, Inc.

Regarding his new position, John commented “BioTools’ technology is at the forefront of vibrational spectrosopy; the products are of the highest quality and their knowledge-based approach & customer relationships are a top priority at BioTools. I am delighted to join the team!”

(Press Release PDF)



BioTools celebrates growth of VCD at Chirality Meeting!

Press Release, Jupiter, FL – July 11, 2012

BioTools celebrates growth of VCD at Chirality Meeting!
Vibrational circular dichroism (VCD), a new tool for determining the absolute configuration of chiral molecules, was a key highlight of the recent 24th International Symposium on Chirality, held June 10-13 in Fort Worth, Texas.  VCD pioneer, BioTools (Jupiter, FL) was on hand, not only sponsoring the exhibitor’s luncheon and the poster awards, but also proudly awarding the Best Poster Given by a Young Scientist for the thirteenth year. Read More Here!


Congratulations to the ISCD Chirality 2012 Poster Awardees!

As a sponsor of the ISCD Chirality 2012 Poster Awards, BioTools would like

to extend our warmest congratulations to the following Awardees
(everyone who presented was a winner!):

1st place – Frank Maier (Universität Heidelberg)
2nd place – Priyanka Lahiri (Yale University)
3rd place – Hili Marom (The Hebrew University of Jerusalem)



Press Release Chiral Technologies & BioTools Partner up


Hot Topics VOA


Dear Researchers,

As the VOA field expands, periodically we
will be featuring papers published in the field.

Recent Published VOA Papers

Absolute configuration reassignment of two chromanes from Peperomia obtusifolia (Piperaceae) using VCD and DFT calculations
João Marcos Batista Jr. a,e, Andrea N. L. Batista a, Daniel Rinaldo a, Wagner Vilegas a, Quezia B. Cass b, Vanderlan S. Bolzani a, Massuo J. Kato c, Silvia N. López a,d, Maysa Furlan a, Laurence A. Nafie e*
a Instituto de Química, Departamento de Química Orgânica, UNESP, Univ Estadual Paulista, C.P. 355, 14800-900, Araraquara, SP, Brazil
b Departamento de Química, Universidade Federal de São Carlos, UFSCar, C.P. 676, 13565-905, São Carlos, SP, Brazil
c Instituto de Química, Universidade de São Paulo, USP, Prof. Lineu Prestes 748 b 11 T, São Paulo, SP, Brazil
d Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK, Rosario, Argentina
e Department of Chemistry, 1-014CST, Syracuse University, Syracuse, NY 13244-4100, USA
Tetrahedron: Asymmetry 21 (2010) 2402-2407
DOI: 10.1016/j.tetasy.2010.09.004
Direct observation and pH control of reversed supramolecular chirality in insulin fibrils by vibrational circular dichroism
Dmitry Kurouski,bRosina A. Lombardi,aRina K. Dukor,cIgor K. Lednev*band
Laurence A. Nafie*ac
a Department of Chemistry, Syracuse University, Syracuse, New York,13244, USA. E-mail:
b Department of Chemistry, University at Albany, SUNY, 1400 Washington Ave., Albany, NY 12222, USA. E-mail:
c BioTools, Inc., 17546 Bee Line Hwy, Jupiter, Florida, 33458, USA. E-mail:
Chem. Commun., 2010, 46, 7154-7156
DOI: 10.1039/c0cc02423f
Chirality transition in the epoxidation of (_)-a-pinene and successive hydrolysis studied by Raman optical activity and DFT
Shi Qiu,abGuanna Li,abPeng Liu, abChanghao Wang, abZhaochi Feng* aand
Can Li*a
a State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. E-mail:,; Fax: +86-411-84694447; Tel: +86-411-84379303, +86-411-84379070
b Graduate University of Chinese Academy of Sciences, Beijing, 100049, China
Phys. Chem. Chem. Phys., 2010, 12, 3005-3013
DOI: 10.1039/b919993d
Vibrational Circular Dichroism of Adsorbed Molecules: BINAS on Gold Nanoparticles
Cyrille Gautierand Thomas Buürgi*
Institut de Physique, Laboratoire de Chimie Physique des Surfaces, UniVersité de Neuchâtel, Rue Emile-Argand
11, 2009 Neuchâtel, Switzerland, and Physikalisch-Chemisches Institut, Ruprecht-Karls-UniVersität Heidelberg,
Im Neuenheimer Feld 253, 69120 Heidelberg, Germany
J. Phys. Chem. C 2010, 114, 15897-15902
DOI: 10.1021/jp910800m
Theoretical Raman Optical Activity Study of the β Domain of Rat Metallothionein
Sandra Luber and Markus Reiher*
Laboratorium für Physikalische Chemie, ETH Zürich, Wolfgang-Pauli-Str. 10, CH-8093 Zürich, Switzerland
J. Phys. Chem. B 2010, 114, 1057-1063
DOI: 10.1021/jp909483q
Directly Probing the Racemization of Imidazolines by Vibrational Circular Dichroism: Kinetics and Mechanism
Shengli Ma, Carl A. Busacca, Keith R. Fandrick, Teresa Bartholomeyzik,
Nizar Haddad, Sherry Shen, Heewon Lee, Anjan Saha, Nathan Yee,
Chris Senanayake, and Nelu Grinberg*
Department of Chemical DeVelopment, Boehringer Ingelheim Pharmaceuticals, Inc.,
Ridgefield, Connecticut 06877
Org. Lett., Vol. 12, No. 12, 2010
DOI: 10.1021/ol100734t
Side Chain and Flexibility Contributions to the Raman Optical Activity Spectra of a Model Cyclic Hexapeptide
Jana Hudecová,Josef Kapitán,Vladimír Baumruk,Robert P. Hammer,
Timothy A. Keiderling,*and Petr Bouř*
Institute of Organic Chemistry and Biochemistry, Academy of Sciences, FlemingoVo nám. 2,
Prague 6, 16610, Czech Republic, Institute of Physics, Charles UniVersity, Ke KarloVu 5, 12116, Prague 2,
Czech Republic, Department of Chemistry, Louisiana State UniVersity, 232 Choppin Hall, Baton Rouge,
Louisiana 70803-1804, and Department of Chemistry, UniVersity of Illinois at Chicago, 845 West Taylor Street, Chicago Illinois 60607-7061
J. Phys. Chem. A 2010, 114, 7642-7651
DOI: 10.1021/jp104744a
Determining the structure of α-phenylethyl isocyanide in chloroform by VCD spectroscopy and DFT calculations-simple case or challenge
Christian Merten,* Marc Amkreutz and Andreas Hartwig
Fraunhofer Institute for Manufacturing Technology and Applied
Materials Research (IFAM), Wiener Strasse 12, 28359 Bremen,
Fax: +49 421 2246 430; Tel: +49 421 2246 515
Phys. Chem. Chem. Phys., 2010, 12, 11635-11641
DOI: 10.1039/c004009f



Ec2 News

to our partner EC2 on a very successful hands-on
Workshop on Vibrational Circular Dichroism!
(May 2012)

Find out more about EC2 The European Centre for Chirality

View the EC2 Brochure:

Ec2 Brochure 1
Ec2 Brochure 2



Hot Topics VOA

HotTopics in VOA - HEADER

Dear Researchers,

As the VOA field expands, we will be featuring
papers published in the field periodically.

Recent Published VOA Papers

Vibrational optical activity

Laurence D. Barron a,*, A. David Buckingham b

a Department of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK

b Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK

Chemical Physics Letters 492 (2010) 199-213


A novel computational method for comparing vibrational

circular dichroism spectra

Jian Shen, Chengyue Zhu, Stephan Reiling, Roy Vaz

Chemical and Analytical Science, Sanofi Aventis Inc., 1041 Route 202-206, Bridgewater, NJ 08807, USA

Spectrochimica Acta Part A 76 (2010) 418-422


Absolute configuration of tropane alkaloids from Schizanthus

species by vibrational circular dichroism

Matías Reina a, Eleuterio Burgueño-Tapia b, María A. Bucio c, Pedro Joseph-Nathan c

a Instituto de Productos Naturales y Agrobiología (IPNA), CSIC, La Laguna, Tenerife, Spain

b Departamento de Química Orgánica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,

Prolongación de Carpio y Plan de  Ayala, Col. Santo Tomás, México, D.F., 11340, Mexico

c Departamento de Química, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico

Nacional, Apartado 14-740, México, D.F., 07000, Mexico

Phytochemistry 71 (2010) 810-815


Conformations of Phenylalanine in the Tripeptides AFA and

GFG Probed by Combining MD Simulations with NMR, FTIR,

Polarized  Raman, and VCD Spectroscopy

Silvia Pizzanelli* a b, Claudia Forte a b, Susanna Montia b, Giorgia Zandomeneghi, c

Andrew Hagarman a b, Thomas J. Measey a b, and Reinhard Schweitzer-Stenner a b

Istituto per i Processi Chimico Fisici, Consiglio Nazionale delle Ricerche, Area della Ricerca di Pisa, Via G. Moruzzi, 1 56124

Pisa, Italy,  Department of Chemistry, Drexel UniVersity, 3141 Chestnut Street, Philadelphia, PennsylVania 19104, and

Laboratory of Physical Chemistry, ETH-Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland

a Area della Ricerca di Pisa,  bDrexel University,  cETH-Zurich
J. Phys. Chem. B 2010, 114, 3965-3978

doi: 10.1021/jp907502n

Conformational analysis and vibrational circular dichroism

study of  a chiral metallocene catalyst

Christian Merten *, Marc Amkreutz, Andreas Hartwig

Fraunhofer Institute for Manufacturing Technology and Applied Materials Research (IFAM), Wiener Strasse 12, 28359

Bremen, Germany

Journal of Molecular Structure 970 (2010) 101-105



BioTools Celebrates 10 Years!

BioTools Inc is celebrating its 10-year
anniversary in 2010. From the start, we
dared to be unique, innovative, and
customer- driven and commercialized two
groundbreaking techniques – VCD and ROA.
We thank everyone who helped us along the
way – customers, vendors and friends.
We invite you to partner with us as we look to
the future and continue to revolutionize the
forefront of vibrational spectroscopy.

17546 Bee Line Hwy ? Jupiter, FL 33458 USA
Tel: 561-625-0133 ? Toll Free: 866-BTOOLS1 ? Fax: 561-625-0717
Email: ? website:

Page 1 of 212